• Gene id: 125488

Gene Summary

• Gene Symbol: TTC39C   Gene   UCSC   Ensembl
• Aliases: C18orf17, HsT2697
• Gene name: tetratricopeptide repeat domain 39C
• Alternate names: tetratricopeptide repeat protein 39C, TPR repeat protein 39C,
• Gene location: 18q11.2 (23992842: 24135969)     Exons: 20     NC_000018.10
• OMIM: 0

Protein Summary

• Protein general information: Q8N584  
  • Name: Tetratricopeptide repeat protein 39C (TPR repeat protein 39C)
  • Length: 583  
  • Mass: 65870
• Sequence:

  MAGSEQQRPRRRDDGDSDAAAAAAAPLQDAELALAGINMLLNNGFRESDQLFKQYRNHSPLMSFGASFVSFLNAM
  MTFEEEKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDVRKSAPSMVDRLQRQIIIADCQVYLAVLSFVKQ
  ELSAYIKGGWILRKAWKIYNKCYLDINALQELYQKKLTEESLTSDAANDNHIVAEGVSEESLNRLKGAVSFGYGL
  FHLCISMVPPNLLKIINLLGFPGDRLQGLSSLMYASESKDMKAPLATLALLWYHTVVRPFFALDGSDNKAGLDEA
  KEILLKKEAAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDS
  FERLKNESRWSQCYYAYLTAVCQGATGDVDGAQIVFKEVQKLFKRKNNQIEQFSVKKAERFRKQTPTKALCVLAS
  IEVLYLWKALPNCSFPNLQRMSQACHEVDDSSVVGLKYLLLGAIHKCLGNSEDAVQYFQRAVKDELCRQNNLYVQ
  PYACYELGCLLLDKPETVGRGRALLLQAKEDFSGYDFENRLHVRIHAALASLRELVPQ

• Structural information:
  • Interpro: IPR019412  IPR011990  
  • STRING: ENSP00000323645
• Other Databases: GeneCards:  TTC39C  Malacards:  TTC39C

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0032474	otolith morphogenesis	IBA	biological process
GO:0060271	cilium assembly	IBA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)