• Gene id: 124817

Gene Summary

• Gene Symbol: CNTD1   Gene   UCSC   Ensembl
• Aliases: CNTD, COSA1
• Gene name: cyclin N-terminal domain containing 1
• Alternate names: cyclin N-terminal domain-containing protein 1,
• Gene location: 17q21.2-q21.31 (42798748: 42811586)     Exons: 8     NC_000017.11
• OMIM: 618166

Protein Summary

• Protein general information: Q8N815  
  • Name: Cyclin N terminal domain containing protein 1
  • Length: 330  
  • Mass: 36921
• Sequence:

  MDGPMRPRSASLVDFQFGVVATETIEDALLHLAQQNEQAVREASGRLGRFREPQIVEFVFLLSEQWCLEKSVSYQ
  AVEILERFMVKQAENICRQATIQPRDNKRESQNWRALKQQLVNKFTLRLVSCVQLASKLSFRNKIISNITVLNFL
  QALGYLHTKEELLESELDVLKSLNFRINLPTPLAYVETLLEVLGYNGCLVPAMRLHATCLTLLDLVYLLHEPIYE
  SLLRASIENSTPSQLQGEKFTSVKEDFMLLAVGIIAASAFIQNHECWSQVVGHLQSITGIALASIAEFSYAILTH
  GVGANTPGRQQSIPPHLAARALKTVASSNT

• Structural information:
  • Protein Domains: (27..17-)
    (/note="Cyclin-N-terminal")
  • Interpro: IPR039890  IPR036915  
  • STRING: ENSP00000465204
• Other Databases: GeneCards:  CNTD1  Malacards:  CNTD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0035861	site of double-strand break	IBA	cellular component
GO:0007131	reciprocal meiotic recombination	IBA	biological process
GO:0007131	reciprocal meiotic recombination	IEA	biological process
GO:0007283	spermatogenesis	IEA	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881