• Gene id: 124044

Gene Summary

• Gene Symbol: SPATA2L   Gene   UCSC   Ensembl
• Aliases: C16orf76, tamo
• Gene name: spermatogenesis associated 2 like
• Alternate names: spermatogenesis-associated protein 2-like protein, SPATA2-like protein,
• Gene location: 16q24.3 (89701704: 89696356)     Exons: 3     NC_000016.10

Protein Summary

• Protein general information: Q8IUW3  
  • Name: Spermatogenesis associated protein 2 like protein (SPATA2 like protein)
  • Length: 424  
  • Mass: 46179
• Sequence:

  MGSSSLSEDYRQCLERELRRGRAGVCGDPSLRAVLWQILVEDFDLHGALQDDALALLTDGLWGRADLAPALRGLA
  RAFELLELAAVHLYLLPWRKEFTTIKTFSGGYVHVLKGVLSDDLLLKSFQKMGYVRRDSHRLMVTALPPACQLVQ
  VALGCFALRLECEILGEVLAQLGTSVLPAEELLQARRASGDVASCVAWLQQRLAQDEEPPPLPPRGSPAAYRAPL
  DLYRDLQEDEGSEDASLYGEPSPGPDSPPAELAYRPPLWEQSAKLWGTGGRAWEPPAEELPQASSPPYGALEEGL
  EPEPSAFSFLSLRRELSRPGDLATPESSAAASPRRIRAEGVPASAYRSVSEPPGYQAHSCLSPGALPTLCCDTCR
  QLHAAHCAALPACRPGHSLRVLLGDAQRRLWLQRAQMDTLLYNSPGARP

• Structural information:
  • STRING: ENSP00000289805
• Other Databases: GeneCards:  SPATA2L  Malacards:  SPATA2L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

KEGG pathways

Pathway id	Pathway name
hsa04217	Necroptosis

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881