• Gene id: 120400

Gene Summary

• Gene Symbol: NXPE1   Gene   UCSC   Ensembl
• Aliases: FAM55A
• Gene name: neurexophilin and PC-esterase domain family member 1
• Alternate names: NXPE family member 1, family with sequence similarity 55, member A, protein FAM55A,
• Gene location: 11q23.2 (114560243: 114518933)     Exons: 11     NC_000011.10
• OMIM: 613476

Protein Summary

• Protein general information: Q8N323  
  • Name: NXPE family member 1 (Protein FAM55A)
  • Length: 547  
  • Mass: 63178
• Sequence:

  MSSNTMLQKTLLILISFSVVTWMIFIISQNFTKLWSALNLSISVHYWNNSAKSLFPKTSLIPLKPLTETELRIKE
  IIEKLDQQIPPRPFTHVNTTTSATHSTATILNPRDTYCRGDQLDILLEVRDHLGQRKQYGGDFLRARMSSPALTA
  GASGKVMDFNNGTYLVSFTLFWEGQVSLSLLLIHPSEGASALWRARNQGYDKIIFKGKFVNGTSHVFTECGLTLN
  SNAELCEYLDDRDQEAFYCMKPQHMPCEALTYMTTRNREVSYLTDKENSLFHRSKVGVEMMKDRKHIDVTNCNKR
  EKIEETCQVGMKPPVPGGYTLQGKWITTFCNQVQLDTIKINGCLKGKLIYLLGDSTLRQWIYYFPKVVKTLKFFD
  LHETGIFKKHLLLDAERHTQIQWKKHSYPFVTFQLYSLIDHDYIPREIDRLSGDKNTAIVITFGQHFRPFPIDIF
  IRRAIGVQKAIERLFLRSPATKVIIKTENIREMHIETERFGDFHGYIHYLIMKDIFKDLNVGIIDAWDMTIAYGT
  DTIHPPDHVIGNQINMFLNYIC

• Structural information:
  • Interpro: IPR013783  IPR014756  IPR026845  
  • STRING: ENSP00000251921
• Other Databases: GeneCards:  NXPE1  Malacards:  NXPE1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005576	extracellular region	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R