• Gene id: 120146

Gene Summary

• Gene Symbol: TRIM64   Gene   UCSC   Ensembl
• Aliases: C11orf28, TRIM64A
• Gene name: tripartite motif containing 64
• Alternate names: tripartite motif-containing protein 64,
• Gene location: 11q14.3 (89966067: 89974146)     Exons: 7     NC_000011.10

Protein Summary

• Protein general information: A6NGJ6  
  • Name: Tripartite motif containing protein 64
  • Length: 449  
  • Mass: 51566
• Sequence:

  MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISEKPNFNTNVVLKKLSS
  LARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEIN
  QETRNNLNQETRTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERM
  KDMYRELWETCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYIS
  LSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCQDSRTADANFVIDSDERF
  FLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT

• Structural information:
  • Protein Domains: (269..44-)
    (/note="B30.2/SPRY-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00548"-)
  • Interpro: IPR001870  IPR003879  IPR013320  IPR003877  IPR000315   IPR018957  IPR001841  IPR013083  IPR017907  
  • Prosite: PS50188 PS50119 PS00518 PS50089
  • CDD: cd00021
  • STRING: ENSP00000483764
• Other Databases: GeneCards:  TRIM64  Malacards:  TRIM64

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0016567	protein ubiquitination	IBA	biological process
GO:0061630	ubiquitin protein ligase activity	IBA	molecular function
GO:0008270	zinc ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)