• Gene id: 118663

Gene Summary

• Gene Symbol: BTBD16   Gene   UCSC   Ensembl
• Aliases: C10orf87
• Gene name: BTB domain containing 16
• Alternate names: BTB/POZ domain-containing protein 16,
• Gene location: 10q26.13 (34186492: 34269343)     Exons: 7     NC_000020.11
• Gene summary(Entrez): This gene encodes a protein that contains a BTB/POZ domain. This domain mediates protein-protein interactions. A mutation in this gene may be associated with bipolar disorder. [provided by RefSeq, Sep 2016]

Protein Summary

• Protein general information: Q32M84  
  • Name: BTB/POZ domain containing protein 16
  • Length: 506  
  • Mass: 58481
• Sequence:

  MIMSNTHKARLERRVTGSTNRWRLPKQPFSGDLLSLSQMCKALSIDFEEALRNPDRLCISQIQKFFFENFKNKDI
  QSGEADVILECLGFKWELHQPQLFQSETLAKLYLKALAQGTTHPLRELEELLRAQSPKKTKEKSPAKRIIISLKI
  NDPLVTKVAFATALKNLYMSEVEINLEDLLGVLASAHILQFSGLFQRCVDVMIARLKPSTIKKFYEAGCKYKEEQ
  LTTGCEKWLEMNLVPLGGTQIHLHKIPQDLLHKVLKSPRLFTFSEFHLLKTMLLWVFLQLNYKIQAIPTYETVMT
  FFKSFPENCCFLDRDIGRSLRPLFLCLRLHGITKGKDLEVLRHLNFFPESWLDQVTVNHYHALENGGDMVHLKDL
  NTQAVRFGLLFNQENTTYSKTIALYGFFFKIKGLKHDTTSYSFYMQRIKHTDLESPSAVYEHNHVSLRAARLVKY
  EIRAEALVDGKWQEFRTNQIKQKFGLTTSSCKSHTLKIQTVGIPIYVSFAFIFPAS

• Structural information:
  • Protein Domains: (150..20-)
    (/note="BTB"-)
  • Interpro: IPR042833  IPR011333  
  • STRING: ENSP00000260723
• Other Databases: GeneCards:  BTBD16  Malacards:  BTBD16

Diseases

Associated diseases	References
Non obstructive azoospermia	MIK: 24012201
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)