• Gene id: 118427

Gene Summary

• Gene Symbol: OLFM3   Gene   UCSC   Ensembl
• Aliases: NOE3, NOELIN3, OPTIMEDIN
• Gene name: olfactomedin 3
• Alternate names: noelin-3, olfactomedin related ER localized protein 3,
• Gene location: 1p21.1 (101997233: 101800027)     Exons: 10     NC_000001.11
• OMIM: 617934

Protein Summary

• Protein general information: Q96PB7  
  • Name: Noelin 3 (Olfactomedin 3) (Optimedin)
  • Length: 478  
  • Mass: 54930
  • Tissue specificity: In the eye, expressed in trabecular meshwork and neural retina; in non-ocular tissues, expressed in brain and lung. {ECO
• Sequence:

  MSPPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLSTPDTLTQISPKEGWQVYSSAQDPDGRCICTVVAPEQN
  LCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKM
  DELLPLIPVLEQYKTDAKLITQFKEEIRNLSAVLTGIQEEIGAYDYEELHQRVLSLETRLRDCMKKLTCGKLMKI
  TGPVTVKTSGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNG
  SLYFNKYQSNIIIKYSFDMGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLN
  QDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARD
  RALYAWNNGHQVLFNVTLFHIIKTEDDT

• Structural information:
  • Protein Domains: (218..47-)
    (/note="Olfactomedin-like-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00446"-)
  • Interpro: IPR031216  IPR022082  IPR003112  IPR011044  
  • Prosite: PS51132
  • STRING: ENSP00000345192
• Other Databases: GeneCards:  OLFM3  Malacards:  OLFM3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0030054	cell junction	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0045202	synapse	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005615	extracellular space	IEA	cellular component
GO:0005794	Golgi apparatus	IEA	cellular component
GO:0042462	eye photoreceptor cell development	IEA	biological process
GO:0032281	AMPA glutamate receptor complex	IEA	cellular component
GO:0045202	synapse	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq