• Gene id: 114787

Gene Summary

• Gene Symbol: GPRIN1   Gene   UCSC   Ensembl
• Aliases: GRIN1
• Gene name: G protein regulated inducer of neurite outgrowth 1
• Alternate names: G protein-regulated inducer of neurite outgrowth 1,
• Gene location: 5q35.2 (176610155: 176595801)     Exons: 2     NC_000005.10

Protein Summary

• Protein general information: Q7Z2K8  
  • Name: G protein regulated inducer of neurite outgrowth 1 (GRIN1)
  • Length: 1008  
  • Mass: 102399
  • Tissue specificity: Widely expressed in the central nervous system, with highest levels in spinal cord. {ECO
• Sequence:

  MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPS
  GAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFL
  EKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKT
  YTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLSGKRDPGPSGKADPM
  PLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLG
  KMDPASSGEGRPVSGHTDTTASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGT
  VSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSE
  KAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEA
  IPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSC
  RKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEP
  KAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVA
  VSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAFPEVRVRPGSALAAA
  VAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKHLERQIEEHGRQGAPAPPPAARAGPGRSGSVRTAP
  PDGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE

• Structural information:
  • Interpro: IPR026646  IPR032745  
  • STRING: ENSP00000305839
• Other Databases: GeneCards:  GPRIN1  Malacards:  GPRIN1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0031175	neuron projection development	IBA	biological process
GO:0005886	plasma membrane	IBA	cellular component
GO:0042995	cell projection	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005886	plasma membrane	IEA	cellular component
GO:0031175	neuron projection development	IEA	biological process
GO:0051219	phosphoprotein binding	IEA	molecular function
GO:0005886	plasma membrane	IEA	cellular component
GO:0030426	growth cone	IEA	cellular component
GO:0005886	plasma membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq