• Gene id: 113655

Gene Summary

• Gene Symbol: MFSD3   Gene   UCSC   Ensembl
• Gene name: major facilitator superfamily domain containing 3
• Alternate names: major facilitator superfamily domain-containing protein 3,
• Gene location: 8q24.3 (144508080: 144511227)     Exons: 4     NC_000008.11
• OMIM: 614357

Protein Summary

• Protein general information: Q96ES6  
  • Name: Major facilitator superfamily domain containing protein 3
  • Length: 412  
  • Mass: 42696
• Sequence:

  MRGKLLPLAGLYLVQGLPYGLQSGLLPVLLRAGGLSLTRVGLAKVLYAPWLLKLAWAPLVDAQGSARAWVTRSTA
  GLGLVCGLLAGLPPPGAGQAGLPAAVAGLLLLLNLGAAMQDVALDALAVQLLEPAELGPGNTVQVVAYKLGAALA
  GGALLALLPTFSWPQLFLLLAATYWLAAALAWAAPALRRLPQQPPSEQRPHTAHLLRDVLAVPGTVWTAGFVLTY
  KLGEQGASSLFPLLLLDHGVSAPELGLWNGVGAVVCSIAGSSLGGTLLAKHWKLLPLLRSVLRFRLGGLACQTAL
  VFHLDTLGASMDAGTILRGSALLSLCLQHFLGGLVTTVTFTGMMRCSQLAPRALQATHYSLLATLELLGKLLLGT
  LAGGLADGLGPHPCFLLLLILSAFPVLYLDLAPSTFL

• Structural information:
  • Interpro: IPR004752  IPR011701  IPR036259  
  • STRING: ENSP00000301327
• Other Databases: GeneCards:  MFSD3  Malacards:  MFSD3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0015295	solute:proton symporter activity	IBA	molecular function
GO:0022857	transmembrane transporter activity	IEA	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0055085	transmembrane transport	IEA	biological process
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component
GO:1902600	proton transmembrane transport	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq