• Gene id: 112611

Gene Summary

• Gene Symbol: RWDD2A   Gene   UCSC   Ensembl
• Aliases: RWDD2, dJ747H23.2
• Gene name: RWD domain containing 2A
• Alternate names: RWD domain-containing protein 2A, RWD domain containing 2,
• Gene location: 6q14.1 (83193354: 83198934)     Exons: 4     NC_000006.12

Protein Summary

• Protein general information: Q9UIY3  
  • Name: RWD domain containing protein 2A
  • Length: 292  
  • Mass: 33893
• Sequence:

  MSASVKESLQLQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYLEGTREALPPKIEFVITLQIEEPKVKIDLQVT
  MPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFDPGELCVCAAIQWLQDNSASYFLNRKLVYEPSTQAKP
  VKNTFLRMWIYSHHIYQQDLRKKILDVGKRLDVTGFCMTGKPGIICVEGFKEHCEEFWHTIRYPNWKHISCKHAE
  SVETEGNGEDLRLFHSFEELLLEAHGDYGLRNDYHMNLGQFLEFLKKHKSEHVFQILFGIESKSSDS

• Structural information:
  • Protein Domains: (14..13-)
    (/note="RWD-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00179"-)
  • Interpro: IPR010541  IPR006575  IPR016135  IPR017359  
  • Prosite: PS50908
  • PDB: 2DAW
  • PDBsum: 2DAW
  • STRING: ENSP00000358739
• Other Databases: GeneCards:  RWDD2A  Malacards:  RWDD2A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)