• Gene id: 10288

Gene Summary

• Gene Symbol: LILRB2   Gene   UCSC   Ensembl
• Aliases: CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10
• Gene name: leukocyte immunoglobulin like receptor B2
• Alternate names: leukocyte immunoglobulin-like receptor subfamily B member 2, CD85 antigen-like family member D, Ig-like transcript 4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, monocyte/macrophage i,
• Gene location: 19q13.42 (54281177: 54273811)     Exons: 15     NC_000019.10
• Gene summary(Entrez): This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular

KEGG pathways

Pathway id	Pathway name
hsa04380	Osteoclast differentiation
hsa04662	B cell receptor signaling pathway

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R