• Gene id: 10233

Gene Summary

• Gene Symbol: LRRC23   Gene   UCSC   Ensembl
• Aliases: LRPB7
• Gene name: leucine rich repeat containing 23
• Alternate names: leucine-rich repeat-containing protein 23, leucine-rich protein B7,
• Gene location: 12p13.31 (6904821: 6914228)     Exons: 8     NC_000012.12
• OMIM: 300295

Protein Summary

• Protein general information: Q53EV4  
  • Name: Leucine rich repeat containing protein 23 (Leucine rich protein B7)
  • Length: 343  
  • Mass: 39761
• Sequence:

  MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLLCKTGNGLAHAYVKLE
  VKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTE
  GISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLT
  TLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLE
  RLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI

• Structural information:
  • Protein Domains: (280..31-)
    (/note="LRRCT"-)
  • Interpro: IPR001611  IPR032675  
  • Prosite: PS51450
  • STRING: ENSP00000390932
• Other Databases: GeneCards:  LRRC23  Malacards:  LRRC23

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005829	cytosol	IBA	cellular component
GO:0005737	cytoplasm	IBA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005829	cytosol	IEA	cellular component
GO:0005575	cellular_component	ND	cellular component
GO:0008150	biological_process	ND	biological process
GO:0003674	molecular_function	ND	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray