|
Gene id |
1000 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
CDH2 Gene UCSC Ensembl |
|
Aliases |
CD325, CDHN, CDw325, NCAD |
|
Gene name |
cadherin 2 |
|
Alternate names |
cadherin-2, N-cadherin 1, cadherin 2, type 1, N-cadherin (neuronal), calcium-dependent adhesion protein, neuronal, neural cadherin, |
|
Gene location |
18q12.1 (28177129: 27932877) Exons: 19 NC_000018.10
|
|
Gene summary(Entrez) |
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell ad
|
|
OMIM |
114020 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa04514 | Cell adhesion molecules | | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | |
|
| Associated diseases |
References |
| Cancer | GAD: 19339270 |
| Cleft defects | GAD: 18978678 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Altered meiotic progression | MIK: 25631347 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25631347 |
Altered me
iotic prog
ression, s
ubfertilit
y
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|